Top 10 Causes of Blood in Stools You Shouldn’t Ignore

Person holding a toilet paper on his left hand and his right hand on his butt.

Key Takeaways

  • Early detection and medical evaluation are essential to prevent complications and ensure timely treatment.
  • Recognizing associated symptoms and risk factors helps differentiate between benign and serious causes.
  • Blood in stools can indicate a wide range of conditions, from minor hemorrhoids to serious gastrointestinal disorders.
  • A structured approach to evaluation, including diagnostic tests, improves patient outcomes.

Noticing blood in stools can be alarming and should never be ignored. The main reason blood in stools warrants prompt medical evaluation is that it may signal underlying gastrointestinal issues ranging from minor hemorrhoids to life‑threatening conditions like colorectal cancer or gastrointestinal bleeding [1]. Identifying the cause early allows for appropriate management and improves outcomes.

Here are the top 10 causes of blood in stools that patients should be aware of.

1. Hemorrhoids

Hemorrhoids, or swollen veins in the rectum or anus, are among the most common causes of blood in stools. They usually result in bright red blood coating the stool or seen on toilet paper, and are often related to straining during bowel movements or chronic constipation [2]. Causes include straining during bowel movements, chronic constipation, or pregnancy. Hemorrhoid-related bleeding is generally painless but may recur if the underlying cause persists.

2. Anal Fissures

Anal fissures are small tears in the lining of the anus, often caused by hard or large stools. Patients may notice bright red blood on the surface of the stool accompanied by sharp pain during bowel movements [3].

3. Diverticulosis

Diverticulosis occurs when small pouches form in the colon wall, which can bleed and cause bloody stools. This bleeding may be intermittent and can require diagnostic imaging or colonoscopy to identify the source [4]. Diverticular bleeding may be intermittent, often requiring diagnostic imaging or colonoscopy to identify the source.

4. Colorectal Polyps

Polyps are abnormal growths on the inner lining of the colon or rectum. Certain polyps can bleed, resulting in rectal bleeding, and early detection through routine screening is important as some polyps may progress to colorectal cancer if left untreated [5].

5. Colorectal Cancer

Colorectal cancer is a serious cause of blood in stools. Blood may appear as streaks on the stool or cause dark, tarry stools if bleeding occurs higher in the colon. Prompt colonoscopy is essential for early diagnosis and treatment [6].

6. Gastrointestinal Infections

Bacterial or viral infections affecting the intestines can cause inflammation and blood in stools. Conditions such as bacterial dysentery or severe gastroenteritis may produce stools that are loose, bloody, and accompanied by abdominal cramps, fever, and nausea. Early medical evaluation ensures appropriate treatment, especially for severe infections.

7. Inflammatory Bowel Disease (IBD)

Inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease, often present with stool with blood. Symptoms may include diarrhea, abdominal pain, urgency, and weight loss. IBD is a chronic condition that requires long-term management and monitoring to prevent complications such as severe bleeding or anemia.

8. Angiodysplasia

Angiodysplasia is a vascular condition where fragile blood vessels in the gastrointestinal tract rupture, causing intermittent blood in stools. It is more common in older adults and may require endoscopic evaluation for diagnosis and treatment. Though often painless, repeated bleeding can lead to anemia.

9. Peptic Ulcers

Peptic ulcers in the stomach or upper small intestine can occasionally lead to blood in stools if the bleeding is significant. Ulcer-related bleeding often results in dark, tarry stools, sometimes accompanied by nausea, vomiting, and abdominal discomfort. Timely diagnosis and treatment reduce the risk of severe blood loss and complications.

10. Angiomas or Vascular Malformations

Rare vascular malformations or benign tumors in the gastrointestinal tract can cause blood in stools. While uncommon, these lesions may bleed intermittently and require diagnostic procedures such as colonoscopy or imaging for identification and management.

Summary Table: Common Causes of Blood in Stools

CauseTypical PresentationAdditional SymptomsNotes
HemorrhoidsBright red blood on stool/toilet paperItching, discomfortOften related to straining
Anal fissuresBright red blood, pain during defecationSharp anal painUsually minor but persistent
DiverticulosisPainless bleeding, sometimes large amountsNone typicallyRequires colonoscopy if recurrent
Colorectal polypsOccasional bleedingUsually asymptomaticEarly detection prevents cancer
Colorectal cancerStreaks or dark stoolsWeight loss, bowel changes, fatigueRequires urgent evaluation
GI infectionsBloody diarrheaFever, cramps, nauseaTreat underlying infection
Inflammatory bowel diseaseBlood with diarrheaAbdominal pain, urgency, weight lossChronic management needed
AngiodysplasiaIntermittent bleedingFatigue if anemia developsCommon in older adults
Peptic ulcersDark/tarry stoolsNausea, vomiting, epigastric painRequires endoscopic treatment
Vascular malformationsIntermittent bleedingOften noneDiagnosis via imaging or endoscopy

When to Seek Medical Attention

Any occurrence of blood in stools should prompt medical evaluation, especially if accompanied by:

  • Persistent or heavy bleeding
  • Abdominal pain or cramping
  • Unexplained weight loss
  • Fatigue or signs of anemia

Diagnostic procedures such as colonoscopy, stool tests, and imaging may be necessary to determine the cause and guide treatment. Early identification of serious conditions like colorectal cancer or IBD improves outcomes.

Preventive Measures

To reduce the risk of conditions causing blood in stools:

  • Maintain a high-fiber diet to prevent constipation and hemorrhoids
  • Stay hydrated and exercise regularly
  • Undergo recommended colonoscopy screening for early detection of polyps or cancer
  • Avoid excessive use of NSAIDs, which may contribute to ulcers
  • Seek timely treatment for gastrointestinal infections

Conclusion

Blood in stools is a symptom that should never be ignored, as it can indicate both minor and serious gastrointestinal conditions. Hemorrhoids, anal fissures, diverticulosis, colorectal polyps, cancer, infections, IBD, vascular conditions, and ulcers are among the top causes.

Recognizing associated symptoms such as abdominal pain, changes in stool color, fatigue, or weight loss helps differentiate serious causes from minor ones. Prompt medical evaluation, appropriate diagnostic testing, and timely intervention are essential to prevent complications and ensure optimal outcomes.

Early attention to blood in stools can save lives, improve quality of life, and reduce the risk of advanced gastrointestinal disease.

References

  1. WebMD. (2024). Blood in stool (hematochezia): Causes, symptoms, and treatment. https://www.webmd.com/digestive-disorders/blood-in-stool
  2. Cleveland Clinic. (2025). Rectal bleeding (blood in stool): Causes, colors & treatments. https://my.clevelandclinic.org/health/symptoms/14612-rectal-bleeding
  3. Harvard Health Publishing. (2025). What can cause blood in stool? https://www.health.harvard.edu/diseases-and-conditions/what-can-cause-blood-in-stool
  4. MedicineNet. (2024). Blood in stool: What it means and how to treat it. https://www.medicine.net/news/Gastroenterology/Blood-in-Stool-What-It-Means-and-How-to-Treat-It.html
  5. GoodRx Health. (2025). Blood in stool causes and symptoms. https://www.goodrx.com/well-being/gut-health/blood-in-your-stool-causes-of-rectal-bleeding
  6. Medical News Today. (2025). Blood in stool: Causes and when to worry. https://www.medicalnewstoday.com/articles/blood-in-stool

Dr Dennis Koh

Clinical Governance Officer

Credits

Dr Koh was a consultant surgeon in the Department of Colorectal Surgery in Singapore General Hospital, one of the most progressive and comprehensive Colorectal Units in Singapore, before setting up his own private practice in 2016. He is also the current Clinical Governance Officer of Curasia Endoscopy Centre.

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